Clinical and histomorphometric comparison of autologous dentin graft versus a deproteinized bovine bone graft for Socket Preservation

Abstract

Dentin has been a significant focus of research due to its potential as a bone substitute, owing to its higher mineral content than any material derived from bone. Additionally, dentin shares two key similarities with autologous bone: it is both osteocompatible and osteoconductive, providing a physical framework for the deposition of new bone. This comparative study assessed the osteoinductive and osteoconductive capabilities of various materials commonly used in “socket preservation” or alveolar ridge preservation. The results showed that the autologous dentin matrix and bovine-derived xenografts (Bio-oss) achieved superior bone regeneration, with a greater volume of newly formed bone (measured by the BV/TV parameter) and reduced fibrous bone, which has undesirable characteristics for implant biomechanics.