Clinical handling and early tissue response of four oral surgery suture materials: a pilot comparative study
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Keywords

oral surgery; sutures; Vicryl Plus; Monocryl; silk; wound healing; dental surgery

Abstract

Background: Suture materials employed in oral surgery vary with respect to their structure, absorbability, coating, handling characteristics, and propensity for plaque retention and tissue reaction. These attributes may impact early wound stability and signs of postoperative inflammation.

Objective: To compare four widely utilized oral surgery suture materials with respect to clinician-rated intraoperative performance and early postoperative clinical response.

Methods: A total of forty patients requiring oral surgical procedures involving suturing were incorporated into a four-arm pilot comparative study. Four types of suture materials were assessed: absorbable monofilament Monocryl 4-0, non-absorbable braided polyester Ethibond Excel 4-0, absorbable antibacterial-coated braided polyglactin 910 Vicryl Plus 4-0, and braided silk 4-0. Follow-up evaluations were conducted at days 3, 7, and 14. Sutures were removed on day 7, including those that are absorbable. The operator rated smoothness, handling, and resistance during placement on a 0-10 scale. Clinical scores for edema, gingival inflammation, perilesional plaque, and suppuration were documented at follow-up.

Results: Monocryl demonstrated the highest mean smoothness score (8.47 ± 0.85) and clinician-rated resistance score (8.92 ± 0.74). Silk exhibited the lowest scores in smoothness (5.60 ± 1.10) and resistance (5.21 ± 0.97), while attaining the highest handling score (7.82 ± 0.95). Early clinical assessments indicated increased edema and inflammation associated with silk at 3 days; conversely, Vicryl Plus showed comparatively low inflammatory scores and low perilesional plaque scores at day 3 and lower scores than silk during follow-up.

Suppuration was infrequent across all groups.

Conclusions: Within the limitations of this pilot dataset, synthetic sutures appeared to provide more favorable intraoperative performance than braided silk, while antibacterial-coated Vicryl Plus showed favorable early clinical scores. The findings should be interpreted cautiously because of the small sample size, incomplete reporting of allocation and ethics procedures, unclear scoring definitions, and absence of microbiological analysis. Larger randomized clinical studies with standardized clinical and microbiological outcomes are required before definitive recommendations can be made.

https://doi.org/10.11138/oi.v18i1.221
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References

Faris A, Khalid L, Hashim M, Yaghi S, Magde T, Bouresly W, et al. Characteristics of suture materials used in oral surgery: systematic review. Int Dent J. 2022;72(3):278-287. doi:10.1016/j.identj.2022.02.005.

La Rosa GRM, Scapellato S, Cicciù M, Pedullà E. Antimicrobial activity of antibacterial sutures in oral surgery: a scoping review. Int Dent J. 2024;74(4):688-695. doi:10.1016/j.identj.2024.01.029.

Selvig KA, Biagiotti GR, Leknes KN, Wikesjö UME. Oral tissue reactions to suture materials. Int J Periodontics Restorative Dent. 1998;18(5):474-487.

Banche G, Roana J, Mandras N, Amasio M, Gallesio C, Allizond V, et al. Microbial adherence on various intraoral suture materials in patients undergoing dental surgery. J Oral Maxillofac Surg. 2007;65(8):1503-1507. doi:10.1016/j.joms.2006.10.066.

Otten JE, Wiedmann-Al-Ahmad M, Jahnke H, Pelz K. Bacterial colonization on different suture materials: a potential risk for intraoral dentoalveolar surgery. J Biomed Mater Res B Appl Biomater. 2005;74B(1):627-635. doi:10.1002/jbm.b.30250.

Kim JS, Shin SI, Herr Y, Park JB, Kwon YH, Chung JH. Tissue reactions to suture materials in the oral mucosa of beagle dogs. J Periodontal Implant Sci. 2011;41(4):185-191. doi:10.5051/jpis.2011.41.4.185.

Sala-Pérez S, López-Ramírez M, Quinteros-Borgarello M, Valmaseda-Castellón E, Gay-Escoda C. Antibacterial suture vs silk for the surgical removal of impacted lower third molars: a randomized clinical study. Med Oral Patol Oral Cir Bucal. 2016;21(1):e95-e102. doi:10.4317/medoral.20721.

Nadafpour N, Montazeri M, Moradi M, Ahmadzadeh S, Etemadi A. Bacterial colonization on different suture materials used in oral implantology: a randomized clinical trial. Front Dent. 2021;18:25. doi:10.18502/fid.v18i25.6935.

Tabrizi R, Mohajerani H, Bozorgmehr F. Polyglactin 910 suture compared with polyglactin 910 coated with triclosan in dental implant surgery: randomized clinical trial. Int J Oral Maxillofac Surg. 2019;48(10):1367-1371. doi:10.1016/j.ijom.2019.01.011.

Asher R, Chacartchi T, Tandlich M, Shapira L, Polak D. Microbial accumulation on different suture materials following oral surgery: a randomized controlled study. Clin Oral Investig. 2019;23(2):559-565. doi:10.1007/s00784-018-2476-0.

Marzo G, Loffredi R, Marchetti E, Di Martino S, Di Pietro C, Marinelli G. In vitro antibacterial efficacy of Vicryl Plus suture (coated Polyglactin 910 with triclosan) using zone of inibition assays. Oral Implantol (Rome). 2008 Apr;1(1):43-

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Copyright (c) 2026 Tommaso Pizzolante, Gianluca Botticelli, Jasmin Gholami Noudeh, Alessia Bianchi, Domenico Marcattili, Elisa Sorrentino, Eugenio Ortale, Sofia Rastelli, Stefano Mummolo